High nasal resistance is stable over time but poorly perceived in people with tetraplegia and obstructive sleep apnoea

NS Wijesuriya; C Lewis; JE Butler; BB Lee; AS Jordan; DJ Berlowitz; DJ Eckert

Journal article

High nasal resistance is stable over time but poorly perceived in people with tetraplegia and obstructive sleep apnoea

NS Wijesuriya, C Lewis, JE Butler, BB Lee, AS Jordan, DJ Berlowitz, DJ Eckert

Respiratory Physiology and Neurobiology | ELSEVIER SCIENCE BV | Published : 2017

DOI: 10.1016/j.resp.2016.09.014

Abstract

Obstructive sleep apnoea (OSA) is highly prevalent in people with tetraplegia. Nasal congestion, a risk factor for OSA, is common in people with tetraplegia. The purpose of this study was to quantify objective and perceived nasal resistance and its stability over four separate days in people with tetraplegia and OSA (n = 8) compared to able-bodied controls (n = 6). Awake nasal resistance was quantified using gold standard choanal pressure recordings (days 1 and 4) and anterior rhinomanometry (all visits). Nasal resistance (choanal pressure) was higher in people with tetraplegia versus controls (5.3[6.5] vs. 2.1[2.4] cmH2O/L/s, p = 0.02) yet perceived nasal congestion (modified Borg score) wa..

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University of Melbourne Researchers

Amy Jordan Author

David Berlowitz Author

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Grants

Awarded by Australian Research Council

Funding Acknowledgements

This work was supported by the National Health and Medical Research Council (NHMRC) of Australia (1065913). DJE is supported by a NHMRC RD Wright Fellowship (1049814). ASJ is supported by an ARC Future Fellowship (FT100100203). JEB is supported by NHMRC Fellowship (1042646). The authors would like to thank the participants of the study for their contribution and the Department of Respiratory Medicine, Prince of Wales hospital, Sydney for loaning their anterior rhinomanometer for the study.